組蛋白H3樣抗體為青島捷世康根據實驗經驗生產，部分試劑盒指標采用美國R&D抗體包被，具有靈敏度高、快速準確、操作方便、易于保存等優點。廣泛用于科研課題研究，臨床對照，以及論文發表。同時提供全程技術服務或免費代測服務（山東省內可上門取樣）。咨詢訂購。購買產品均有積分相贈（同一單位可累計）可兌換手機、筆記本電腦等禮品

產品型號：50ul;100ul

更新時間：2024-12-26

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品牌	其他品牌	純度	100
貨號	bs-0483R	規格	50u;100ul
供貨周期	現貨	主要用途	科研實驗
應用領域	醫療衛生,化工,生物產業,綜合

基本信息

產品編號	bs-0483R
英文名稱	Rabbit Anti-Centromeric histone H3-like protein-2 antibody
中文名稱	組蛋白H3樣抗體
別名	centromere-specific H3 variant protein; Centromeric histone H3-like protein 2; Centromeric histone H3-like protein-2; cenp-A; A4PIF1_BRAJU.
產品類型	植物抗體
組蛋白H3樣抗體研究領域	腫瘤免疫學發育生物學轉錄調節因子植物
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	(predicted: Brassica juncea)
產品應用	IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
理論分子量	20kDa
細胞定位	細胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from Brassica juncea Centromeric histone H3-like protein-2: 3-19/178
亞型	IgG
純化方法	affinity purified by Protein A
緩沖液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
產品介紹	Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.